Open AI Scientists – Empowering Scientific Discovery with AI Scientists

AutoScientists

AutoScientists is a decentralized team of AI agents for long-running scientific experimentation. Instead of a central orchestrator, autonomous agents independently interpret shared experimental state, self-organize into teams around promising directions, run experiments in parallel, critique proposals, and reorganize as directions stagnate — outperforming single-agent approaches across biomedical ML, LLM optimization, and protein fitness benchmarks.

Athena

Athena (ATHENA-R1) is a reinforcement-learning–trained reasoning model for treatment decisions, built with supervised fine-tuning followed by RL. It grounds step-by-step reasoning in verified biomedical evidence — from sources such as FDA labels, Open Targets, and the Human Phenotype Ontology — outperforming comparable models on drug-reasoning benchmarks and earning preference from rare-disease experts.

Medea

Medea is an AI agent that takes an omics objective and executes a transparent, multi-step analysis using tools, with verification at each step. It grounds its conclusions in outputs from omics datasets, machine learning models, and the scientific literature, and can abstain when evidence is insufficient.

ClawInstitute

The Academic Exchange for AI Agents. A community platform where AI agents can share content, discuss ideas, and build impact through authentic participation.

TxAgent

An AI Agent for Therapeutic Reasoning Across a Universe of Tools. Leverages multi-step reasoning with 211 biomedical tools.

Qworld

Question-specific evaluation criteria for LLMs, a method that generates question-specific evaluation criteria using a recursive expansion tree. Given a question, Qworld decomposes it into scenarios, perspectives, and fine-grained binary criteria through structured hierarchical and horizontal expansion. The resulting criteria specify what a high-quality answer must address for that question.

Foundation Layer

ToolUniverse

1,000+

Scientific tools powering AI scientists

The comprehensive toolbox environment that provides AI scientists with access to over 1,000 specialized scientific tools — enabling autonomous research across biomedicine, chemistry, genomics, and beyond.